9/21/2023 0 Comments Nexium heart burnThese trials were registered at : NCT01370525 NCT01370538.Įsomeprazole antacid durability of effects heartburn proton-pump inhibitor symptomatic rebound treatment satisfaction. Esomeprazole's treatment effect was maintained for ≥ one week after treatment ended, with no sign of symptomatic rebound. Nexium is used to treat symptoms of gastroesophageal reflux disease (GERD) and other conditions involving excessive stomach acid such as Zollinger-Ellison syndrome. Subjects who are likely to self-treat their frequent heartburn with over-the-counter medications reported satisfaction with esomeprazole 20 mg. Nexium is a proton pump inhibitor that decreases the amount of acid produced in the stomach. Significantly more subjects taking esomeprazole were "very satisfied" or "satisfied" with treatment versus placebo (Study 1: 78% vs. Some research has also shown improved symptoms in people with GERD who take. Rescue antacid use generally decreased compared with the run-in period in the 14-day treatment and 1-week follow-up periods. However, peppermint is traditionally used for alleviating: colds. The percentage of heartburn-free days was maintained during the 1-week follow-up period the proportion was 43% among esomeprazole subjects in these studies, suggesting no evidence of symptomatic rebound. The percentage of heartburn-free days during the 1-week follow-up, use of rescue antacids, and treatment satisfaction, measured with the Global Assessment Questions instrument, are described. It provides the same complete protection from frequent heartburn in easy-to-swallow tablets. Get 24-hour relief from frequent heartburn with Nexium 24HR Tablets. The results of the primary efficacy endpoints were reported previously. Buy Now Get Coupons 24-hour protection in an easy-to-swallow tablet. All subjects entered a 1-week single-blind placebo follow-up period after treatment. These analyses were conducted to assess durability of effects and symptomatic rebound after cessation of treatment, treatment satisfaction, and rescue antacid use with esomeprazole 20 mg once daily for 14 days.Īdults with frequent heartburn (≥ two days/week in the past four weeks) were randomly assigned to 14 days of double-blind treatment with esomeprazole 20 mg or placebo in two identical multicenter studies. Esomeprazole 20 mg once daily has been shown to be effective for treating frequent heartburn over 14 days in subjects who are likely to self-treat with over-the-counter medications.
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